Mutual repression between steroid and xenobiotic receptor and NF-κB signaling pathways links xenobiotic metabolism and inflammation

While it has long been known that inflammation and infection reduce expression of hepatic cytochrome P450 (CYP) genes involved in xenobiotic metabolism and that exposure to xenobiotic chemicals can impair immune function, the molecular mechanisms underlying both of these phenomena have remained larg...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zhou, Changcheng, Tabb, Michelle M., Nelson, Edward L., Grün, Felix, Verma, Suman, Sadatrafiei, Asal, Lin, Min, Mallick, Shyamali, Forman, Barry M., Thummel, Kenneth E., Blumberg, Bruce
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2006
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501109/
https://ncbi.nlm.nih.gov/pubmed/16841097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26283
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