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The orphan GPR50 receptor specifically inhibits MT(1) melatonin receptor function through heterodimerization

One-third of the ∼400 nonodorant G protein-coupled receptors (GPCRs) are still orphans. Although a considerable number of these receptors are likely to transduce cellular signals in response to ligands that remain to be identified, they may also have ligand-independent functions. Several members of...

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Detalhes bibliográficos
Main Authors: Levoye, Angélique, Dam, Julie, Ayoub, Mohammed A, Guillaume, Jean-Luc, Couturier, Cyril, Delagrange, Philippe, Jockers, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500982/
https://ncbi.nlm.nih.gov/pubmed/16778767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601193
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