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Biosynthesis of tumorigenic HER2 C-terminal fragments by alternative initiation of translation
The overactivation of the HERs, a family of tyrosine kinase receptors, leads to the development of cancer. Although the canonical view contemplates HER receptors restricted to the secretory and endocytic pathways, full-length HER1, HER2 and HER3 have been detected in the nucleoplasm. Furthermore, li...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1500971/ https://ncbi.nlm.nih.gov/pubmed/16794579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601191 |
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