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The Individualization of Cancer Therapy: The Unexpected Role of p53

Our laboratory discovered that p53 can regulate the sensitivity to cancer therapies by affecting three critical aspects of cancer pharmacology: 1). The expression of drug targets; 2). the access of drugs to intracellular targets; and the response to DNA damage. We review the effects of p53 on antimi...

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Detalles Bibliográficos
Main Authors: Hait, William N, Yang, Jin-Ming
Formato: Artigo
Idioma:Inglês
Publicado: American Clinical and Climatological Association 2006
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500917/
https://ncbi.nlm.nih.gov/pubmed/18528466
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