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Role of p53 isoforms and aggregations in cancer
p53 is a master regulatory protein that is involved in diverse cellular metabolic processes such as apoptosis, DNA repair, and cell cycle arrest. The protective function of p53 (in its homotetrameric form) as a tumor suppressor is lost in more than 50% of human cancers. Despite considerable experime...
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| Publicado no: | Medicine (Baltimore) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wolters Kluwer Health
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4937917/ https://ncbi.nlm.nih.gov/pubmed/27368003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000003993 |
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