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p53 Isoforms and Their Implications in Cancer

In this review we focus on the major isoforms of the tumor-suppressor protein p53, dysfunction of which often leads to cancer. Mutations of the TP53 gene, particularly in the DNA binding domain, have been regarded as the main cause for p53 inactivation. However, recent reports demonstrating abundanc...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancers (Basel)
Main Authors: Vieler, Maximilian, Sanyal, Suparna
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162399/
https://ncbi.nlm.nih.gov/pubmed/30149602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10090288
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