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An unexpected role for p53 in regulating cancer cell–intrinsic PD-1 by acetylation
Cancer cell–intrinsic programmed cell death protein-1 (PD-1) has emerged as a tumor regulator in an immunity-independent manner, but its precise role in modulating tumor behaviors is complex, and how PD-1 is regulated in cancer cells is largely unknown. Here, we identified PD-1 as a direct target of...
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| 出版年: | Sci Adv |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Association for the Advancement of Science
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8011965/ https://ncbi.nlm.nih.gov/pubmed/33789902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abf4148 |
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