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Two conformations of a crystalline human tRNA synthetase–tRNA complex: implications for protein synthesis
Aminoacylation of tRNA is the first step of protein synthesis. Here, we report the co-crystal structure of human tryptophanyl-tRNA synthetase and tRNA(Trp). This enzyme is reported to interact directly with elongation factor 1α, which carries charged tRNA to the ribosome. Crystals were generated fro...
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Hoofdauteurs: | , , , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2006
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1500858/ https://ncbi.nlm.nih.gov/pubmed/16724112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601154 |
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