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In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine

Social isolation (SI) of male mice lasting >4 weeks is associated with aggression toward intruders and a down-regulation of brain allopregnanolone (Allo) content. SI of female mice fails to down-regulate brain Allo content or to induce aggressiveness. Fluoxetine (Prozac in clinical use) is an S-...

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書誌詳細
主要な著者: Pinna, Graziano, Dong, Erbo, Matsumoto, Kinzo, Costa, Erminio, Guidotti, Alessandro
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC149954/
https://ncbi.nlm.nih.gov/pubmed/12571361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0337642100
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