Allopregnanolone: From molecular pathophysiology to therapeutics. A historical perspective

Allopregnanolone is synthesized in the central nervous system either de novo from cholesterol or from steroid hormone precursors like progesterone and pregnenolone. Over the past 30 years, direct and rapid, non-genomic actions of allopregnanolone and its derivatives via GABA(A) receptors have been d...

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Detalhes bibliográficos
Publicado no:Neurobiol Stress
Main Authors: Paul, Steven M, Pinna, Graziano, Guidotti, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Articles from the Special Issue on Allopregnanolone role in the neurobiology of stress and mood disorders; Edited by Graziano Pinna
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7231972/
https://ncbi.nlm.nih.gov/pubmed/32435665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynstr.2020.100215
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