Allopregnanolone: From molecular pathophysiology to therapeutics. A historical perspective

Allopregnanolone is synthesized in the central nervous system either de novo from cholesterol or from steroid hormone precursors like progesterone and pregnenolone. Over the past 30 years, direct and rapid, non-genomic actions of allopregnanolone and its derivatives via GABA(A) receptors have been d...

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Publicat a:Neurobiol Stress
Autors principals: Paul, Steven M, Pinna, Graziano, Guidotti, Alessandro
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Articles from the Special Issue on Allopregnanolone role in the neurobiology of stress and mood disorders; Edited by Graziano Pinna
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7231972/
https://ncbi.nlm.nih.gov/pubmed/32435665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynstr.2020.100215
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