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In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine

Social isolation (SI) of male mice lasting >4 weeks is associated with aggression toward intruders and a down-regulation of brain allopregnanolone (Allo) content. SI of female mice fails to down-regulate brain Allo content or to induce aggressiveness. Fluoxetine (Prozac in clinical use) is an S-...

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Detalhes bibliográficos
Main Authors: Pinna, Graziano, Dong, Erbo, Matsumoto, Kinzo, Costa, Erminio, Guidotti, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149954/
https://ncbi.nlm.nih.gov/pubmed/12571361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0337642100
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