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Tracking an embryonic L1 retrotransposition event

Long interspersed nuclear elements 1 (L1) are active retrotransposons that reside in many species, including humans and rodents. L1 elements produce an RNA intermediate that is reverse transcribed to DNA and inserted in a new genomic location. We have tagged an active human L1 element (L1(RP)) with...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Prak, Eline T. Luning, Dodson, Allen W., Farkash, Evan A., Kazazian, Haig H.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149919/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12569170/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0337627100
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