Histone deacetylation by Sir2 generates a transcriptionally repressed nucleoprotein complex

Sir2 is an NAD-dependent histone deacetylase required for transcriptional silencing. To study the mechanism of Sir2 function, we examined the biochemical properties of purified recombinant Drosophila Sir2 (dSir2). First, we performed histone deacetylation assays and found that dSir2 deacetylates a b...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Parsons, Xuejun Huang, Garcia, Sandra N., Pillus, Lorraine, Kadonaga, James T.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 2003
Aiheet:	Biological Sciences
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149880/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12571358/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0434064100
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!