Binding of small molecules to an adaptive protein–protein interface

Understanding binding properties at protein–protein interfaces has been limited to structural and mutational analyses of natural binding partners or small peptides identified by phage display. Here, we present a high-resolution analysis of a nonpeptidyl small molecule, previously discovered by medic...

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Autors principals: Arkin, Michelle R., Randal, Mike, DeLano, Warren L., Hyde, Jennifer, Luong, Tinh N., Oslob, Johan D., Raphael, Darren R., Taylor, Lisa, Wang, Jun, McDowell, Robert S., Wells, James A., Braisted, Andrew C.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC149879/
https://ncbi.nlm.nih.gov/pubmed/12582206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252756299
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