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Tetrameric Oligomerization of IκB Kinase γ (IKKγ) Is Obligatory for IKK Complex Activity and NF-κB Activation

The IκB kinase (IKK) complex mediates activation of transcription factor NF-κB by phosphorylation of IκB proteins. Its catalytic subunits, IKKα and IKKβ, require association with the regulatory IKKγ (NEMO) component to gain full basal and inducible kinase activity. However, the oligomeric compositio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tegethoff, Sebastian, Behlke, Joachim, Scheidereit, Claus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC149477/
https://ncbi.nlm.nih.gov/pubmed/12612076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.6.2029-2041.2003
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