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Tetrameric Oligomerization of IκB Kinase γ (IKKγ) Is Obligatory for IKK Complex Activity and NF-κB Activation

The IκB kinase (IKK) complex mediates activation of transcription factor NF-κB by phosphorylation of IκB proteins. Its catalytic subunits, IKKα and IKKβ, require association with the regulatory IKKγ (NEMO) component to gain full basal and inducible kinase activity. However, the oligomeric compositio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Tegethoff, Sebastian, Behlke, Joachim, Scheidereit, Claus
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2003
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC149477/
https://ncbi.nlm.nih.gov/pubmed/12612076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.6.2029-2041.2003
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