Tetrameric Oligomerization of IκB Kinase γ (IKKγ) Is Obligatory for IKK Complex Activity and NF-κB Activation

The IκB kinase (IKK) complex mediates activation of transcription factor NF-κB by phosphorylation of IκB proteins. Its catalytic subunits, IKKα and IKKβ, require association with the regulatory IKKγ (NEMO) component to gain full basal and inducible kinase activity. However, the oligomeric compositio...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Tegethoff, Sebastian, Behlke, Joachim, Scheidereit, Claus
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2003
Témata:	Cell Growth and Development
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149477/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12612076/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.6.2029-2041.2003
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