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Effect of human leukocyte antigen heterozygosity on infectious disease outcome: The need for allele-specific measures

BACKGROUND: Doherty and Zinkernagel, who discovered that antigen presentation is restricted by the major histocompatibility complex (MHC, called HLA in humans), hypothesized that individuals heterozygous at particular MHC loci might be more resistant to particular infectious diseases than the corres...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:BMC Med Genet
Hauptverfasser: Lipsitch, Marc, Bergstrom, Carl T, Antia, Rustom
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2003
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149356/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12542841/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2350-4-2
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