Effect of human leukocyte antigen heterozygosity on infectious disease outcome: The need for allele-specific measures

BACKGROUND: Doherty and Zinkernagel, who discovered that antigen presentation is restricted by the major histocompatibility complex (MHC, called HLA in humans), hypothesized that individuals heterozygous at particular MHC loci might be more resistant to particular infectious diseases than the corres...

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Bibliografiske detaljer

Udgivet i:	BMC Med Genet
Principais autores:	Lipsitch, Marc, Bergstrom, Carl T, Antia, Rustom
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2003
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149356/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12542841/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2350-4-2
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