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Effect of human leukocyte antigen heterozygosity on infectious disease outcome: The need for allele-specific measures

BACKGROUND: Doherty and Zinkernagel, who discovered that antigen presentation is restricted by the major histocompatibility complex (MHC, called HLA in humans), hypothesized that individuals heterozygous at particular MHC loci might be more resistant to particular infectious diseases than the corres...

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書目詳細資料
發表在:BMC Med Genet
Principais autores: Lipsitch, Marc, Bergstrom, Carl T, Antia, Rustom
格式: Artigo
語言:Inglês
出版: BMC 2003
主題:
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149356/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12542841/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2350-4-2
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