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Effect of human leukocyte antigen heterozygosity on infectious disease outcome: The need for allele-specific measures
BACKGROUND: Doherty and Zinkernagel, who discovered that antigen presentation is restricted by the major histocompatibility complex (MHC, called HLA in humans), hypothesized that individuals heterozygous at particular MHC loci might be more resistant to particular infectious diseases than the corres...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149356/ https://ncbi.nlm.nih.gov/pubmed/12542841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-4-2 |
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