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Amino Acid Sequence Requirements at Residues 69 and 238 for the SME-1 β-Lactamase To Confer Resistance to β-Lactam Antibiotics
Carbapenem antibiotics have been used to counteract resistant strains of bacteria harboring β-lactamases and extended-spectrum β-lactamases. Four enzymes from the class A group of β-lactamases, NMC-A, IMI-1, SME-1, and KPC-1, efficiently hydrolyze carbapenem antibiotics. Sequence comparisons and str...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149323/ https://ncbi.nlm.nih.gov/pubmed/12604542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.3.1062-1067.2003 |
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