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Amino Acid Residues That Contribute to Substrate Specificity of Class A β-Lactamase SME-1
Carbapenem antibiotics are used as antibiotics of last resort because they possess a broad spectrum of antimicrobial activity and are not easily hydrolyzed by β-lactamases. Recently, class A enzymes, such as the SME-1, NMC-A, and IMI-1 β-lactamases, have been identified with the capacity to hydrolyz...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1196253/ https://ncbi.nlm.nih.gov/pubmed/16048956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.8.3421-3427.2005 |
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