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Does the HIV-1 primer activation signal interact with tRNA(3)(Lys) during the initiation of reverse transcription?

Reverse transcription of HIV-1 RNA is primed by a tRNA(3)(Lys) molecule bound at the primer binding site (PBS). Complex intermolecular interactions were proposed between tRNA(3)(Lys) and the RNA of the HIV-1 Mal isolate. Recently, an alternative interaction was proposed between the TΨC stem of tRNA(...

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Bibliographic Details
Main Authors: Goldschmidt, Valérie, Ehresmann, Chantal, Ehresmann, Bernard, Marquet, Roland
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC149207/
https://ncbi.nlm.nih.gov/pubmed/12560480
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