Does the HIV-1 primer activation signal interact with tRNA(3)(Lys) during the initiation of reverse transcription?

Reverse transcription of HIV-1 RNA is primed by a tRNA(3)(Lys) molecule bound at the primer binding site (PBS). Complex intermolecular interactions were proposed between tRNA(3)(Lys) and the RNA of the HIV-1 Mal isolate. Recently, an alternative interaction was proposed between the TΨC stem of tRNA(...

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Publié dans:	Nucleic Acids Res
Auteurs principaux:	Goldschmidt, Valérie, Ehresmann, Chantal, Ehresmann, Bernard, Marquet, Roland
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 2003
Sujets:	Articles
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149207/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12560480/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg187
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