Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases
Retroviruses are RNA viruses that replicate through a DNA intermediate, in a process catalyzed by the viral reverse transcriptase (RT). Although cellular polymerases and host factors contribute to retroviral mutagenesis, the RT errors play a major role in retroviral mutation. RT mutations that affec...
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| Autore principale: | |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI AG
2009-12-01
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| Serie: | Viruses |
| Soggetti: | |
| Accesso online: | http://www.mdpi.com/1999-4915/1/3/1137/ |
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