Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases
Retroviruses are RNA viruses that replicate through a DNA intermediate, in a process catalyzed by the viral reverse transcriptase (RT). Although cellular polymerases and host factors contribute to retroviral mutagenesis, the RT errors play a major role in retroviral mutation. RT mutations that affec...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI AG
2009-12-01
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| Serier: | Viruses |
| Fag: | |
| Online adgang: | http://www.mdpi.com/1999-4915/1/3/1137/ |
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