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ERVK Polyprotein Processing and Reverse Transcriptase Expression in Human Cell Line Models of Neurological Disease

Enhanced expression of the reverse transcriptase (RT) protein encoded by human endogenous retrovirus-K (ERVK) is a promising biomarker for several inflammatory and neurological diseases. However, unlike RT enzymes encoded by exogenous retroviruses, little work has been done to identify ERVK RT isofo...

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Principais autores: Mamneet Manghera, Jennifer Ferguson, Renée Douville
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2015-01-01
Serier:Viruses
Fag:
endogenous retrovirus
reverse transcriptase
astrocyte
neuron
neurological disease
inflammation
IFNγ
Online adgang:http://www.mdpi.com/1999-4915/7/1/320
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