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New role of zCRY and zPER2 as regulators of sub-cellular distributions of zCLOCK and zBMAL proteins

The core oscillator that generates circadian rhythm in eukaryotes consists of transcription/translation-based autoregulatory feedback loops by which clock gene products negatively regulate their own expression. Control of the accumulation and nuclear entry of the negative regulators PER and CRY is b...

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Main Authors: Hirayama, Jun, Fukuda, Itsuki, Ishikawa, Tomoko, Kobayashi, Yuri, Todo, Takeshi
格式: Artigo
語言:Inglês
出版: Oxford University Press 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC149195/
https://ncbi.nlm.nih.gov/pubmed/12560489
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