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Functional consequences of mutations in the conserved SF2 motifs and post-translational phosphorylation of the CSB protein

The rare inherited human genetic disorder Cockayne syndrome (CS) is characterized by developmental abnormalities, UV sensitivity and premature aging. The cellular and molecular phenotypes of CS include increased sensitivity to UV-induced and oxidative DNA lesions. Two genes are involved: CSA and CSB...

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Autors principals: Christiansen, Mette, Stevnsner, Tinna, Modin, Charlotte, Martensen, Pia M., Brosh, Robert M., Bohr, Vilhelm A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC149186/
https://ncbi.nlm.nih.gov/pubmed/12560492
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