Differential Role of β(1C) and β(1A) Integrin Cytoplasmic Variants in Modulating Focal Adhesion Kinase, Protein Kinase B/AKT, and Ras/Mitogen-activated Protein Kinase Pathways

The integrin cytoplasmic domain modulates cell proliferation, adhesion, migration, and intracellular signaling. The β(1) integrin subunits, β(1C) and β(1A), that contain variant cytoplasmic domains differentially affect cell proliferation; β(1C) inhibits proliferation, whereas β(1A) promotes it. We...

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Hlavní autoři: Fornaro, Mara, Steger, Craig A., Bennett, Anton M., Wu, J. Julie, Languino, Lucia R.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC14916/
https://ncbi.nlm.nih.gov/pubmed/10888665
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