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Structure of human cystathionine β-synthase: a unique pyridoxal 5′-phosphate-dependent heme protein
Cystathionine β-synthase (CBS) is a unique heme- containing enzyme that catalyzes a pyridoxal 5′-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased le...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149156/ https://ncbi.nlm.nih.gov/pubmed/11483494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.3910 |
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