Structure of human cystathionine β-synthase: a unique pyridoxal 5′-phosphate-dependent heme protein

Cystathionine β-synthase (CBS) is a unique heme- containing enzyme that catalyzes a pyridoxal 5′-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased le...

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Bibliographic Details
Main Authors: Meier, Markus, Janosik, Miroslav, Kery, Vladimir, Kraus, Jan P., Burkhard, Peter
Format: Artigo
Language:Inglês
Published: Oxford University Press 2001
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC149156/
https://ncbi.nlm.nih.gov/pubmed/11483494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.3910
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