High Impact of an Expanded Restriction Fragment Length Polymorphism Assay on Detection of Ganciclovir-Resistant UL97 Mutants of Human Cytomegalovirus

Eitemau Tebyg

• A Nine-Codon Deletion Mutation in the Cytomegalovirus UL97 Phosphotransferase Gene Confers Resistance to Ganciclovir
  gan: Chou, Sunwen, et al.
  Cyhoeddwyd: (2000)
• A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate.
  gan: Baldanti, F, et al.
  Cyhoeddwyd: (1995)
• The Cys607→Tyr Change in the UL97 Phosphotransferase Confers Ganciclovir Resistance to Two Human Cytomegalovirus Strains Recovered from Two Immunocompromised Patients
  gan: Baldanti, Fausto, et al.
  Cyhoeddwyd: (1998)
• Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recovered from patients with AIDS.
  gan: Baldanti, F, et al.
  Cyhoeddwyd: (1996)
• A point mutation in the human cytomegalovirus DNA polymerase gene confers resistance to ganciclovir and phosphonylmethoxyalkyl derivatives.
  gan: Sullivan, V, et al.
  Cyhoeddwyd: (1993)