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Site-Specific Mutagenesis Analysis of PBP 1A from a Penicillin-Cephalosporin-Resistant Pneumococcal Isolate

Our mutagenesis study has investigated all amino acid mutations in the penicillin-binding domain of PBP 1A from Hungarian pneumococcal isolate 3191 to determine the importance of every mutation in the development of penicillin and cefotaxime resistance. Our data reveal that mutations at amino acid p...

詳細記述

保存先:
書誌詳細
主要な著者: Smith, Anthony M., Klugman, Keith P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC149026/
https://ncbi.nlm.nih.gov/pubmed/12499220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.1.387-389.2003
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