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Alterations in PBP 1A Essential for High-Level Penicillin Resistance in Streptococcus pneumoniae
High-level penicillin resistance in pneumococci is due to alterations in penicillin-binding proteins (PBPs) 2X, 2B, and 1A. We have sequenced the penicillin-binding domain of PBP 1A from penicillin-resistant South African pneumococcal isolates and have identified amino acid substitutions which are c...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
1998
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC105597/ https://ncbi.nlm.nih.gov/pubmed/9624469 |
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