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Alterations in PBP 1A Essential for High-Level Penicillin Resistance in Streptococcus pneumoniae

High-level penicillin resistance in pneumococci is due to alterations in penicillin-binding proteins (PBPs) 2X, 2B, and 1A. We have sequenced the penicillin-binding domain of PBP 1A from penicillin-resistant South African pneumococcal isolates and have identified amino acid substitutions which are c...

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Bibliografische gegevens
Hoofdauteurs: Smith, Anthony M., Klugman, Keith P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 1998
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC105597/
https://ncbi.nlm.nih.gov/pubmed/9624469
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