Alterations in PBP 1A Essential for High-Level Penicillin Resistance in Streptococcus pneumoniae
High-level penicillin resistance in pneumococci is due to alterations in penicillin-binding proteins (PBPs) 2X, 2B, and 1A. We have sequenced the penicillin-binding domain of PBP 1A from penicillin-resistant South African pneumococcal isolates and have identified amino acid substitutions which are c...
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| Published in: | Antimicrob Agents Chemother |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1998
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105597/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9624469/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.6.1329 |
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