Altered PBP 2A and Its Role in the Development of Penicillin, Cefotaxime, and Ceftriaxone Resistance in a Clinical Isolate of Streptococcus pneumoniae

We report the unusual involvement of altered PBP 2A in the development of β-lactam resistance in Streptococcus pneumoniae. This was investigated amid three identical serotype 14 isolates (designated isolates 1, 2, and 3, respectively) of pneumococci cultured successfully from the blood of a human im...

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Detalhes bibliográficos
Main Authors: Smith, Anthony M., Feldman, Charles, Massidda, Orietta, McCarthy, Kerrigan, Ndiweni, Dalu, Klugman, Keith P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087663/
https://ncbi.nlm.nih.gov/pubmed/15855525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.2002-2007.2005
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