Alcohol Dehydrogenase Restricts the Ability of the Pathogen Candida albicans To Form a Biofilm on Catheter Surfaces through an Ethanol-Based Mechanism

Candida biofilms formed on indwelling medical devices are increasingly associated with severe infections. In this study, we used proteomics and Western and Northern blotting analyses to demonstrate that alcohol dehydrogenase (ADH) is downregulated in Candida biofilms. Disruption of ADH1 significantl...

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Bibliografiske detaljer
Main Authors: Mukherjee, Pranab K., Mohamed, Sotohy, Chandra, Jyotsna, Kuhn, Duncan, Liu, Shuqing, Antar, Omar S., Munyon, Ryan, Mitchell, Aaron P., Andes, David, Chance, Mark R., Rouabhia, Mahmoud, Ghannoum, Mahmoud A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489753/
https://ncbi.nlm.nih.gov/pubmed/16790752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00161-06
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