Alcohol Dehydrogenase Restricts the Ability of the Pathogen Candida albicans To Form a Biofilm on Catheter Surfaces through an Ethanol-Based Mechanism

Candida biofilms formed on indwelling medical devices are increasingly associated with severe infections. In this study, we used proteomics and Western and Northern blotting analyses to demonstrate that alcohol dehydrogenase (ADH) is downregulated in Candida biofilms. Disruption of ADH1 significantl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Mukherjee, Pranab K., Mohamed, Sotohy, Chandra, Jyotsna, Kuhn, Duncan, Liu, Shuqing, Antar, Omar S., Munyon, Ryan, Mitchell, Aaron P., Andes, David, Chance, Mark R., Rouabhia, Mahmoud, Ghannoum, Mahmoud A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489753/
https://ncbi.nlm.nih.gov/pubmed/16790752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00161-06
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge