A Monoclonal Antibody to Bacillus anthracis Protective Antigen Defines a Neutralizing Epitope in Domain 1

Antibody (Ab) responses to Bacillus anthracis toxins are protective, but relatively few protective monoclonal antibodies (MAbs) have been reported. Protective antigen (PA) is essential for the action of B. anthracis lethal toxin (LeTx) and edema toxin. In this study, we generated two MAbs to PA, MAb...

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Détails bibliographiques
Auteurs principaux: Rivera, Johanna, Nakouzi, Antonio, Abboud, Nareen, Revskaya, Ekaterina, Goldman, David, Collier, R. John, Dadachova, Ekaterina, Casadevall, Arturo
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Molecular Pathogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489699/
https://ncbi.nlm.nih.gov/pubmed/16790789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00150-06
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