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Immunogenicity of Bacillus anthracis Protective Antigen Domains and Efficacy of Elicited Antibody Responses Depend on Host Genetic Background

Neutralizing antibodies to Bacillus anthracis protective antigen (PA), a component of anthrax toxin, mediate protection against anthrax. PA is antigenically complex and can elicit protective and nonprotective antibodies. Furthermore, vaccinated individuals demonstrate considerable variability in the...

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Detalhes bibliográficos
Main Authors: Abboud, Nareen, Casadevall, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446646/
https://ncbi.nlm.nih.gov/pubmed/18480236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00015-08
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