A Monoclonal Antibody to Bacillus anthracis Protective Antigen Defines a Neutralizing Epitope in Domain 1

Antibody (Ab) responses to Bacillus anthracis toxins are protective, but relatively few protective monoclonal antibodies (MAbs) have been reported. Protective antigen (PA) is essential for the action of B. anthracis lethal toxin (LeTx) and edema toxin. In this study, we generated two MAbs to PA, MAb...

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Bibliographische Detailangaben
Hauptverfasser: Rivera, Johanna, Nakouzi, Antonio, Abboud, Nareen, Revskaya, Ekaterina, Goldman, David, Collier, R. John, Dadachova, Ekaterina, Casadevall, Arturo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Molecular Pathogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489699/
https://ncbi.nlm.nih.gov/pubmed/16790789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00150-06
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