A Monoclonal Antibody to Bacillus anthracis Protective Antigen Defines a Neutralizing Epitope in Domain 1

Antibody (Ab) responses to Bacillus anthracis toxins are protective, but relatively few protective monoclonal antibodies (MAbs) have been reported. Protective antigen (PA) is essential for the action of B. anthracis lethal toxin (LeTx) and edema toxin. In this study, we generated two MAbs to PA, MAb...

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Detalhes bibliográficos
Main Authors: Rivera, Johanna, Nakouzi, Antonio, Abboud, Nareen, Revskaya, Ekaterina, Goldman, David, Collier, R. John, Dadachova, Ekaterina, Casadevall, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489699/
https://ncbi.nlm.nih.gov/pubmed/16790789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00150-06
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