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A Monoclonal Antibody to Bacillus anthracis Protective Antigen Defines a Neutralizing Epitope in Domain 1

Antibody (Ab) responses to Bacillus anthracis toxins are protective, but relatively few protective monoclonal antibodies (MAbs) have been reported. Protective antigen (PA) is essential for the action of B. anthracis lethal toxin (LeTx) and edema toxin. In this study, we generated two MAbs to PA, MAb...

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Bibliografiska uppgifter
Huvudupphovsmän: Rivera, Johanna, Nakouzi, Antonio, Abboud, Nareen, Revskaya, Ekaterina, Goldman, David, Collier, R. John, Dadachova, Ekaterina, Casadevall, Arturo
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2006
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489699/
https://ncbi.nlm.nih.gov/pubmed/16790789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00150-06
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