Penetration of Dihydroartemisinin into Cerebrospinal Fluid after Administration of Intravenous Artesunate in Severe Falciparum Malaria

Penetration of cerebrospinal fluid (CSF) by artesunate and DHA was assessed in six adults with cerebral or severe malaria. Lumbar punctures were performed on admission and during convalescence, at 15 min (patient 1), 30 min (patient 2), 45 min (patient 3), 60 min (patient 4), 90 min (patient 5), and...

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Autors principals: Davis, Timothy M. E., Binh, Tran Quang, Ilett, Kenneth F., Batty, Kevin T., Phuöng, Hoang Lan, Chiswell, Gregory M., Bich Phuong, Vu Duong, Agus, Cindy
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC148951/
https://ncbi.nlm.nih.gov/pubmed/12499215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.1.368-370.2003
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