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Penetration of Dihydroartemisinin into Cerebrospinal Fluid after Administration of Intravenous Artesunate in Severe Falciparum Malaria

Penetration of cerebrospinal fluid (CSF) by artesunate and DHA was assessed in six adults with cerebral or severe malaria. Lumbar punctures were performed on admission and during convalescence, at 15 min (patient 1), 30 min (patient 2), 45 min (patient 3), 60 min (patient 4), 90 min (patient 5), and...

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Hlavní autoři: Davis, Timothy M. E., Binh, Tran Quang, Ilett, Kenneth F., Batty, Kevin T., Phuöng, Hoang Lan, Chiswell, Gregory M., Bich Phuong, Vu Duong, Agus, Cindy
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC148951/
https://ncbi.nlm.nih.gov/pubmed/12499215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.1.368-370.2003
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