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Steady-State Pharmacokinetics of Amprenavir Coadministered with Ritonavir in Human Immunodeficiency Virus Type 1-Infected Patients

The protease inhibitor (PI) ritonavir is used as a strong inhibitor of cytochrome P450 3A4, which boosts the activities of coadministered PIs, resulting in augmented plasma PI levels, simplification of the dosage regimen, and better efficacy against resistant viruses. The objectives of the present o...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Goujard, Cecile, Vincent, Isabelle, Meynard, Jean-Luc, Choudet, Nathalie, Bollens, Diane, Rousseau, Cyril, Demarles, Didier, Gillotin, Catherine, Bidault, Roselyne, Taburet, Anne-Marie
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148948/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12499178/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.1.118-123.2003
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