Steady-State Pharmacokinetics of Amprenavir Coadministered with Ritonavir in Human Immunodeficiency Virus Type 1-Infected Patients

The protease inhibitor (PI) ritonavir is used as a strong inhibitor of cytochrome P450 3A4, which boosts the activities of coadministered PIs, resulting in augmented plasma PI levels, simplification of the dosage regimen, and better efficacy against resistant viruses. The objectives of the present o...

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Hlavní autoři: Goujard, Cecile, Vincent, Isabelle, Meynard, Jean-Luc, Choudet, Nathalie, Bollens, Diane, Rousseau, Cyril, Demarles, Didier, Gillotin, Catherine, Bidault, Roselyne, Taburet, Anne-Marie
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC148948/
https://ncbi.nlm.nih.gov/pubmed/12499178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.1.118-123.2003
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