Steady-State Pharmacokinetics of Amprenavir Coadministered with Ritonavir in Human Immunodeficiency Virus Type 1-Infected Patients

The protease inhibitor (PI) ritonavir is used as a strong inhibitor of cytochrome P450 3A4, which boosts the activities of coadministered PIs, resulting in augmented plasma PI levels, simplification of the dosage regimen, and better efficacy against resistant viruses. The objectives of the present o...

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Detalhes bibliográficos
Main Authors: Goujard, Cecile, Vincent, Isabelle, Meynard, Jean-Luc, Choudet, Nathalie, Bollens, Diane, Rousseau, Cyril, Demarles, Didier, Gillotin, Catherine, Bidault, Roselyne, Taburet, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC148948/
https://ncbi.nlm.nih.gov/pubmed/12499178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.1.118-123.2003
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