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The Assembly and Maintenance of Heterochromatin Initiated by Transgene Repeats Are Independent of the RNA Interference Pathway in Mammalian Cells

A role for the RNA interference (RNAi) pathway in the establishment of heterochromatin is now well accepted for various organisms. Less is known about its relevance and precise role in mammalian cells. We previously showed that tandem insertion of a 1,000-copy inducible transgene into the genome of...

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Hlavní autoři: Wang, Fangwei, Koyama, Naoki, Nishida, Hiroko, Haraguchi, Tokuko, Reith, Walter, Tsukamoto, Toshiro
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489094/
https://ncbi.nlm.nih.gov/pubmed/16705157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02189-05
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